Thermo Fisher Scientific NMBR Polyclonal Antibody
NMBR 단백질을 인식하는 Rabbit Polyclonal 항체로 Western blot 및 IHC에 사용 가능. 인간, 마우스, 설치류 등 다양한 종에 반응. 합성 펩타이드 항원을 사용하여 제작. 동결건조 형태로 제공되며 장기 보관 시 -20°C 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500 | - |
| Immunohistochemistry (IHC) | 1:500 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / Ig |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide from mouse NMBR conjugated to blue carrier protein was used as the antigen |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | Not Determined |
| Storage Buffer | Whole serum |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. Glycerol (1:1) may be added for added stability. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
- The peptide is homologous in rat, human, and marmoset.
- Specificity: NMBR.
Target Information
NMBR (neuromedin B receptor) is a Bombesin Receptor that activates phospholipase and protein kinase C, enhancing calcium mobilization. It binds neuromedin B, a potent mitogen and growth factor for normal and neoplastic lung and gastrointestinal epithelial tissues.
Expression has been reported in brain (olfactory bulb and thalamus), colon, liver, placenta, testis, spinal cord, and gastrointestinal tract. It is also present in cancers of the lung, ovary, and prostate. ESTs have been isolated from B-cell/lung/testis and brain libraries.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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