Thermo Fisher Scientific CEA (CEACAM5) Monoclonal Antibody (OTI9F9), TrueMAB
Human CEACAM5(CD66e) 인식 단클론 항체로 Western blot에 적합. Mouse IgG2b 아이소타입이며, 비표지 상태의 동결건조 형태. PBS 및 trehalose 완충액에 보관되며, -20°C에서 저장. 연구용으로만 사용 가능.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific CEA (CEACAM5) Monoclonal Antibody (OTI9F9), TrueMAB
Applications
- Western Blot (WB): Tested dilution 1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI9F9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 35–680 of human CEACAM5 produced in SF9 cell (target family: CD66e (CEACAM5), UniProt ID: P06731-1) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
- For conjugation experiments, perform an additional desalting step (recommended: Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CEA (Carcinoembryonic Antigen, CD66e) is synthesized during fetal development in the gut and re-expressed in intestinal carcinomas and other tumors. It belongs to the immunoglobulin superfamily, consisting of one N-domain and six constant-like domains (A1–A3, B1–B3).
Antibodies to CEA help identify the origin of metastatic adenocarcinomas and distinguish pulmonary adenocarcinomas (60–70% CEA+) from pleural mesotheliomas (rarely or weakly CEA+).
CEA functions as a cell adhesion molecule involved in tissue differentiation, angiogenesis, apoptosis, tumor suppression, metastasis, and immune response modulation. Multiple transcript variants exist, though not all are fully characterized.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.