Thermo Fisher Scientific NOTCH3 Recombinant Superclonal Antibody (4HCLC)

Applications

• Western Blot (WB): 1–2 µg/mL

Product Specifications

Product Specific Information

This antibody is predicted to react with Monkey, Bovine, Cat, and Rat.

Recombinant rabbit Superclonal™ antibodies are unique offerings from Thermo Fisher Scientific. They consist of multiple recombinant monoclonal antibodies, combining the sensitivity of polyclonal antibodies with the specificity of monoclonal antibodies.
They offer consistent performance across lots due to their defined recombinant composition, eliminating biological variability typical of polyclonal production.

Note: Formerly called “Recombinant polyclonal antibody”, now rebranded as “Recombinant Superclonal™ antibody”. Physical product and performance remain unchanged.

Target Information

NOTCH3 is a human homologue of the Drosophila type I membrane protein notch. In Drosophila, notch interactions with ligands (delta, serrate) regulate neural development.
In humans, NOTCH3 functions as a receptor for ligands Jagged1, Jagged2, and Delta1 to regulate cell-fate determination.
Mutations in NOTCH3 are associated with cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.