Thermo Fisher Scientific NCoR1 Monoclonal Antibody (7A7A9)
Thermo Fisher Scientific의 NCoR1 Monoclonal Antibody (7A7A9)은 인간 시료에서 NCoR1 단백질을 검출하기 위한 항체입니다. Western blot, IHC, ELISA 등에 적합하며, 고순도 재조합 항원으로 제작되었습니다. 장기 보관 시 -20°C에서 안정적으로 유지됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:1,000 | - |
| Immunocytochemistry (ICC/IF) | - | View 1 publication |
| ELISA | 1:10,000 | View 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7A7A9 |
| Immunogen | Purified recombinant fragment of NCOR1 (aa1–192) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term; for long-term storage, store at -20°C and avoid freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_11009317 |
Product Specific Information
MA5-15447 targets NCoR1 in indirect ELISA, IHC, and WB applications and shows reactivity with human samples.
The immunogen is a purified recombinant fragment of NCoR1 (aa1–192) expressed in E. coli.
Target Information
The NCoR1 gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery.
It is part of a complex including histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p.
This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17.
Alternate splicing results in multiple transcript variants, and pseudogenes are found on chromosomes 17 and 20.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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