Thermo Fisher Scientific p300 Monoclonal Antibody (7D8A6)
인간 EP300 단백질을 타겟으로 하는 Mouse IgG1 단일클론 항체입니다. Western blot과 ELISA에 사용 가능하며, 비결합형 액상 형태로 제공됩니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용됩니다.
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Thermo Fisher Scientific p300 Monoclonal Antibody (7D8A6)
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| ELISA | 1:10,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 7D8A6 |
| Immunogen | Purified recombinant fragment of EP300 expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term storage, store at -20°C, avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_10977116 |
Product Specific Information
MA5-15444 targets EP300 in indirect ELISA and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of EP300 expressed in E. coli.
Target Information
EP300 encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein.
p300 is related by sequence to CPB (CREB-binding protein, cyclic-AMP responsive element binding protein), and like CPB, can stimulate transcription through activation of CREB.
This EP300 activity is specifically inhibited by the adenovirus oncoprotein E1A.
EP300 also acts as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), contributing to the stimulation of hypoxia-induced genes such as VEGF.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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