Thermo Fisher Scientific SOX2 Monoclonal Antibody (10F10C9)
SOX2 단백질을 인식하는 마우스 단클론 항체로, Western blot, ICC/IF, ELISA에 적합합니다. 인간 시료에 반응하며, 줄기세포 유지 및 발달 관련 연구에 유용합니다. 액상 형태로 제공되며 4°C 또는 -20°C에서 보관 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| ELISA | 1:10,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 10F10C9 |
| Immunogen | Purified recombinant fragment of SOX2 (aa1–170) expressed in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | Not determined |
| Storage Buffer | Ascites |
| Contains | 0.03% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_10976833 |
Product Specific Information
MA5-15449 targets SOX2 in indirect ELISA and WB applications, showing reactivity with human samples.
The immunogen is a purified recombinant fragment of SOX2 (aa1–170) expressed in E. coli.
MA5-15449 detects SOX2, which has a predicted molecular weight of approximately 34.3 kDa.
Target Information
SOX2 is an intronless gene encoding a member of the SRY-related HMG-box (SOX) family of transcription factors involved in embryonic development and cell fate determination.
The SOX2 protein is essential for stem-cell maintenance in the central nervous system and regulates gene expression in the stomach.
SOX2 lies within an intron of another gene, SOX2 overlapping transcript (SOX2OT).
It may act as a transcriptional activator by forming complexes with other proteins.
Mutations in the SOX2 gene are associated with bilateral anophthalmia, optic nerve hypoplasia, and syndromic microphthalmia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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