Thermo Fisher Scientific CD36 (Platelet and Microvessel Marker) Monoclonal Antibody (1A7)
인간 CD36 단백질을 인식하는 마우스 단클론 항체로, 혈소판 및 미세혈관 마커 연구에 적합. ICC/IF, Flow Cytometry, Functional Assay에 사용 가능. 단백질 A/G로 정제된 액상 항체이며, 보존제 무첨가. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunocytochemistry (ICC/IF) | 1–2 µg/mL |
| Flow Cytometry (Flow) | 1–2 µg/10⁶ cells |
| Functional Assay | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A7 |
| Immunogen | Human CD36 from platelets |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD36, also known as scavenger receptor class B member 3, is a protein expressed on the surface of various cell types including macrophages, platelets, and adipocytes. It plays important roles in lipid metabolism, inflammation, and atherosclerosis, and participates in recognition and uptake of ligands such as oxidized LDL, long-chain fatty acids, and apoptotic cells.
CD36 also acts as a receptor for thrombospondin and is the fourth major glycoprotein on the platelet surface. It binds collagen, thrombospondin, anionic phospholipids, and oxidized LDL, mediating cytoadherence of Plasmodium falciparum-infected erythrocytes.
Mutations in this gene can cause platelet glycoprotein deficiency. Multiple alternatively spliced transcript variants exist. Diseases associated with CD36 include Platelet Glycoprotein IV Deficiency and Coronary Heart Disease 7.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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