Thermo Fisher Scientific CARMA1 Polyclonal Antibody
CARMA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 인간 및 마우스에서 반응 예측. 액상 형태, 1 mg/mL 농도, 4°C 보관.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 275 and 325 of human card-maguk protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, functioning as a molecular scaffold for multiprotein complexes at specialized regions of the plasma membrane.
It is also a member of the CARD protein family, characterized by a caspase-associated recruitment domain (CARD).
This protein has a domain structure similar to CARD14 and interacts specifically with BCL10, which regulates cell apoptosis and NF-kappaB activation.
Expression of this protein in cells activates NF-kappaB and induces BCL10 phosphorylation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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