Thermo Fisher Scientific CARMA1 Polyclonal Antibody
CARMA1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 인간 및 마우스에서 반응 예측. 액상 형태로 4°C 보관, 1년 권장 보관 기간.
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 475 and 525 of human CARD-MAGUK protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse
Target Information
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, functioning as molecular scaffolds for multiprotein complex assembly at specialized plasma membrane regions. It is also part of the CARD protein family, characterized by the caspase-associated recruitment domain (CARD). CARD domains of CARD11 and CARD14 specifically interact with BCL10, a positive regulator of cell apoptosis and NF-κB activation. When expressed, this protein activates NF-κB and induces phosphorylation of BCL10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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