Thermo Fisher Scientific CARMA1 Polyclonal Antibody
CARMA1 단백질을 표적으로 하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western Blot 및 Immunoprecipitation에 적합하며 Human에 반응. 액상 형태로 4°C 보관, 항원 친화 크로마토그래피로 정제됨. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 475 and 525 of human card-maguk protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse
Target Information
The protein encoded by this gene belongs to the membrane-associated guanylate kinase (MAGUK) family, functioning as a molecular scaffold for multiprotein complex assembly at specialized regions of the plasma membrane.
It is also a member of the CARD protein family, defined by a caspase-associated recruitment domain (CARD).
This protein has a domain structure similar to CARD14 and interacts specifically with BCL10, a positive regulator of cell apoptosis and NF-kappaB activation.
Expression of this protein activates NF-kappaB and induces phosphorylation of BCL10.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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