
Thermo Fisher Scientific PDE3B Polyclonal Antibody, Biotin
PDE3B 단백질을 인식하는 Biotin 결합 폴리클로날 항체로, WB, IHC, ICC, ELISA, IP 등 다양한 응용에 사용 가능. Rabbit 유래 IgG 형식이며, Human, Mouse, Rat 등 여러 종에 반응. Affinity chromatography로 정제되어 높은 특이성과 재현성을 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Chicken, Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a unique amino acid sequence on the PDE3B gene |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cyclic nucleotide phosphodiesterase with dual specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. It may play a role in fat metabolism and regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6, it assembles a signaling complex that activates the PI3K gamma complex via RAPGEF3, contributing to angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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