Thermo Fisher Scientific PDE3B Polyclonal Antibody, FITC
PDE3B 단백질을 인식하는 FITC 결합 폴리클로날 항체로, WB, IHC, ICC/IF, ELISA, IP 등 다양한 응용에 적합합니다. Rabbit IgG 기반으로 높은 특이성과 감도를 제공합니다. cAMP/cGMP 관련 신호전달 연구에 활용 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| Immunocytochemistry (ICC/IF) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
| Immunomicroscopy (IM) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Chicken, Human, Mouse, Non-human primate, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 1050–2000 on mouse PDE3B protein. Labels all variants of PDE3B. |
| Conjugate | FITC (Fluorescein) |
| Excitation/Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 30% glycerol, 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | –20°C, store in dark |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Cyclic nucleotide phosphodiesterase with dual specificity for the second messengers cAMP and cGMP, which are key regulators of many physiological processes. May play a role in fat metabolism and regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6, it assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and is involved in angiogenesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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