Thermo Fisher Scientific I-Ek Monoclonal Antibody (14-4-4S)

Applications

Tested Dilution

Publications

Flow Cytometry (Flow)

1 µg/1 million cells

-

Product Specifications

Species Reactivity

Mouse

Host/Isotype

Mouse / IgG2a, kappa

Class

Monoclonal

Type

Antibody

Clone

14-4-4S

Immunogen

C3H. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MHC Class II (I-Ek),uniProtId:P04230-1,ncbiNodeId:10090,antigenRange:1-264,antigenLength:264,antigenImageFileName:MA1-70066_MHC_Class_II_I-Ek_P04230-1_House_mouse.svg,antigenImageFileNamePDP:MA1-70066_MHC_Class_II_I-Ek_P04230-1_House_mouse_PDP.jpeg,sortOrder:1},{targetFamily:MHC Class II (I-Ek),uniProtId:P14439-1,ncbiNodeId:10090,antigenRange:1-255,antigenLength:255,antigenImageFileName:MA1-70066_MHC_Class_II_I-Ek_P14439-1_House_mouse.svg,antigenImageFileNamePDP:MA1-70066_MHC_Class_II_I-Ek_P14439-1_House_mouse_PDP.jpeg,sortOrder:2}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

View additional formats

• Biotin
• FITC
• PE
• Request custom conjugation

Form

Liquid

Concentration

1 mg/mL

Purification

Protein G

Storage buffer

PBS

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1076836

Product Specific Information

MA1-70066 detects I-Ek in mouse samples.

MA1-70066 has been successfully used in flow cytometry and cytotoxicity studies.

The MA1-70066 immunogen is C3H.

Target Information

MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on the surface of professional antigen-presenting cells, such as macrophages, dendritic cells and B cells. Before their exposition on the cell surface, the MHC class II molecules react with endocytosed exogenous antigens, which are then presented to the T cells. The antigen-binding grove between MHC class II alpha and beta chain is open at both ends and is 15-24 amino acid residues long.

HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.