Thermo Fisher Scientific I-Ek Monoclonal Antibody (14-4-4S)
Thermo Fisher Scientific의 I-Ek Monoclonal Antibody (14-4-4S)는 마우스 시료에서 I-Ek 검출에 사용되는 비결합 항체입니다. Flow cytometry 및 세포독성 연구에 적합하며, 1 mg/mL 농도의 액상 형태로 제공됩니다. Protein G로 정제되어 안정적이며 -20°C에서 보관합니다.
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Applications
Flow Cytometry (Flow)
- Tested Dilution: 1 µg/1 million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 14-4-4S |
| Immunogen | C3H |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1076836 |
Additional Formats
Product Specific Information
MA1-70066 detects I-Ek in mouse samples.
It has been successfully used in flow cytometry and cytotoxicity studies.
The immunogen is derived from C3H.
Target Information
MHC (major histocompatibility complex) class II molecules are transmembrane glycoproteins expressed on professional antigen-presenting cells such as macrophages, dendritic cells, and B cells.
Before exposure on the cell surface, these molecules bind endocytosed exogenous antigens, which are then presented to T cells.
The antigen-binding groove between the alpha and beta chains is open at both ends and accommodates peptides 15–24 amino acids long.
HLA and MHC antibodies are crucial in Immunopeptidomics, enabling identification and characterization of neoantigens through LC-MS/MS analysis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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