Thermo Fisher Scientific IP3R1 Polyclonal Antibody
IP3R1 단백질을 표적하는 Rabbit Polyclonal 항체로, Western blot과 Immunoprecipitation에 적합합니다. Human에 반응하며 Mouse, Rat, Bovine에서도 예측 반응합니다. 항원 친화 크로마토그래피로 정제된 액상 형태로, TBS buffer에 보관됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1025 and 1050 of human inositol 1,4,5-trisphosphate receptor type 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, predicted to react with Mouse, Rat, and Bovine
Target Information
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate.
Involved in the regulation of epithelial secretion of electrolytes and fluid through interaction with AHCYL1.
Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis via activation of CaM kinase II, leading to downstream apoptosis pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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