
Thermo Fisher Scientific IP3R1 Polyclonal Antibody
IP3R1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot 및 Immunoprecipitation에 적합하며, 인간, 마우스, 랫트, 소에서 반응 예측. 액상 형태로 4°C 보관, 연구용 전용.
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Thermo Fisher Scientific IP3R1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunoprecipitation (IP) | 2–5 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1025 and 1050 of human inositol 1,4,5-trisphosphate receptor type 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Predicted to react with Mouse, Rat, and Bovine based on 100% sequence identity
Target Information
Intracellular channel that mediates calcium release from the endoplasmic reticulum following stimulation by inositol 1,4,5-trisphosphate.
Involved in the regulation of epithelial secretion of electrolytes and fluid through interaction with AHCYL1.
Plays a role in ER stress-induced apoptosis. Cytoplasmic calcium released from the ER triggers apoptosis by activating CaM kinase II, which leads to downstream apoptosis pathways.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송 정보
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