
Thermo Fisher Scientific CLASP2 Polyclonal Antibody
CLASP2 단백질을 인식하는 Thermo Fisher의 토끼 폴리클로날 항체로, Western blot 및 면역침강(IP)에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: Assay-dependent
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 and 50 of human cytoplasmic linker associated protein 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
CLASP2 is a microtubule plus-end tracking protein that promotes the stabilization of dynamic microtubules. It is required for the polarization of cytoplasmic microtubule arrays in migrating cells toward the leading edge. CLASP2 acts at the cell cortex to enhance the rescue frequency of depolymerizing microtubules by attaching their plus-ends to cortical platforms composed of ERC1 and PHLDB2. This activity is regulated in part by phosphatidylinositol 3-kinase signaling. CLASP2 also stabilizes microtubules at the kinetochore, essential for bipolar chromosome alignment on the mitotic spindle.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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