Thermo Fisher Scientific FOLH1/PSMA Monoclonal Antibody (FOLH1, 3734)
FOLH1/PSMA 단백질을 인식하는 Mouse monoclonal 항체로 Western blot, IHC(P), Peptide Array에 사용 가능. 다양한 종에 반응하며, Protein A/G로 정제된 액상형 항체. 인간 전립선암 연구 및 PSMA 관련 단백질 분석에 적합.
- 카탈로그번호
- 2346-MSM6-P1
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1–2 µg/mL |
| Peptide Array (Array) | Assay-dependent |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Bovine, Dog, Horse, Cat, Human, Mouse |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | FOLH1, 3734 |
| Immunogen | Recombinant fragment (aa 44–177) of human FOLH1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): Incubate antibody for 30 minutes at room temperature.
- For formalin-fixed tissues: Heat sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, then cool at room temperature for 20 minutes.
Target Information
This gene encodes a type II transmembrane glycoprotein of the M28 peptidase family. It functions as a glutamate carboxypeptidase acting on substrates such as folate and N-acetyl-L-aspartyl-L-glutamate. Expression occurs in prostate, nervous system, and kidney tissues. Mutations may lead to impaired folate absorption and hyperhomocysteinemia. In the prostate, the protein is upregulated in cancerous cells and serves as a diagnostic and prognostic marker for prostate cancer. Alternative splicing produces multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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