Thermo Fisher Scientific MUC16/CA125 Monoclonal Antibody (OCA125, 1900)
인간 MUC16/CA125 단백질을 인식하는 단클론 항체로, IHC(P)에서 1–2 µg/mL 농도로 사용 가능. Mouse IgG1, kappa 형식이며 Protein A/G로 정제된 액상 형태. 4°C 보관, 연구용으로만 사용.
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Applications
- Immunohistochemistry (Paraffin) (IHC (P)): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host/Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OCA125, 1900 |
| Immunogen | Full length native MUC16 protein purified from human ovarian carcinoma |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- Immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
- Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
CA125 determinant is present on a high molecular weight, mucin-like glycoprotein.
It is found on frozen sections of amnion and derivatives of coelomic and mullerian epithelium, including pleura, pericardium, and peritoneum.
In adult tissues, expression is observed in epithelial cells of fallopian tube, endometrium, endocervix, pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland, and mammary gland.
Also found in mesothelial cell lining of pleura, pericardium, and peritoneum, as well as ovarian tumors of serous, endometrioid, or clear cell types and adenocarcinomas of mullerian type.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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