Thermo Fisher Scientific MUC16/CA125 Monoclonal Antibody (OCA125, 1900)

Applications

• Immunohistochemistry (Paraffin) (IHC (P))

Tested Dilution: 1–2 µg/mL
Publications: -

Product Specifications

Product Specific Information

Immunohistochemistry (PFA fixed):

• Incubate antibody for 30 min at room temperature.
• Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA (pH 9.0) for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.

Target Information

CA125 determinant is present on a high molecular weight, mucin-like glycoprotein.
It is found on frozen sections of amnion and derivatives of coelomic and mullerian epithelium, including pleura, pericardium, and peritoneum.
In adult tissues, expression is observed in epithelial cells of fallopian tube, endometrium, endocervix, pancreas, colon, gall bladder, stomach, kidney, apocrine sweat gland, and mammary gland.
It is also found in mesothelial cell lining of pleura, pericardium, and peritoneum, as well as in ovarian tumors of serous, endometrioid, or clear cell types and adenocarcinomas of mullerian type.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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