Thermo Fisher Scientific FAM3B/PANDER Polyclonal Antibody
FAM3B/PANDER 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat에 반응하며, Protein A로 정제된 액상 형태입니다. -20°C에서 보관하며 연구용으로 사용됩니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from mouse FAM3B (amino acids 1–100) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FAM3B (family with sequence similarity 3, member B), also known as ORF9, C21orf11, or PANDER, is a 235 amino acid secreted protein localized to vesicular and perinuclear structures. It is highly expressed in the pancreas and at lower levels in kidney, colon, testis, prostate, and small intestine. FAM3B functions as an islet-specific cytokine that promotes apoptosis and may inhibit insulin secretion from beta-cells, potentially influencing pancreatic activity.
Human FAM3B shares 78% sequence identity with the mouse counterpart, indicating a conserved role across species. Three isoforms (A, B, and C) exist due to alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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