Thermo Fisher Scientific Kappa Light Chain (B-Cell Marker) Monoclonal Antibody (HP6053, L1C1)
인간 Kappa Light Chain을 표적하는 단클론 항체로 B세포 마커 검출에 적합. Western blot 및 면역조직화학(IHC) 응용 가능. Protein A/G 정제, 액상 형태, 4°C 보관. 연구용으로만 사용.
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2개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific Kappa Light Chain (B-Cell Marker) Monoclonal Antibody (HP6053, L1C1)
Thermo Fisher Scientific Kappa Light Chain (B-Cell Marker) Monoclonal Antibody (HP6053, L1C1)
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (PFA fixed) (IHC (PFA)) | 1–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | HP6053, L1C1 |
| Immunogen | Purified human Ig kappa chain (HP6053) & Human B-Lymphoma Cells (L1C1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Immunoglobulin classes share the same basic four polypeptide chain structure of two heavy chains and two light chains (kappa, lambda). Kappa and lambda light chains have variable and constant regions and are differentiated by their antigenic properties. The kappa to lambda ratio is approximately 70:30. Antibodies to the kappa light chain are useful in identifying leukemias, plasmacytomas, and certain non-Hodgkin’s lymphomas. Demonstration of clonality in lymphoid infiltrates indicates malignancy.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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