Thermo Fisher Scientific LRP1 Recombinant Rabbit Monoclonal Antibody (ARC0275)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:5,000-1:30,000

-

Immunocytochemistry (ICC/IF)

1:200

-

ELISA (ELISA)

1 µg/mL

-

Immunoprecipitation (IP)

Assay-dependent

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC0275

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 4400-4500 of human LRP1 (Q07954) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LRP1 (CD91),uniProtId:Q07954-1,ncbiNodeId:9606,antigenRange:4400-4500,antigenLength:4544,antigenImageFileName:MA5-35053_LRP1_CD91_Q07954-1_Rabbit.svg,antigenImageFileNamePDP:MA5-35053_LRP1_CD91_Q07954-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2848958

Product Specific Information

Immunogen sequence: PPHMTGPRCE EHVFSQQQPG HIASILIPLL LLLLLVLVAG VVFWYKRRVQ GAKGFQHQRM TNGAMNVEIG NPTYKMYEGG EPDDVGGLLD ADFALDPDKP T

Target Information

The protein encoded by this gene is an endocytic receptor involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the A2M-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer patients.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.