Thermo Fisher Scientific Bestrophin 3 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Bestrophin-3 protein. Validated for WB, ELISA, and IP applications. High specificity and affinity purified. Suitable for research use in bovine, human, and primate samples.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Bovine, Human, Non-human primate |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide taken within the last 50 amino acids from the C-terminus of human Bestrophin-3 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
BEST3 belongs to the bestrophin family of anion channels, which includes BEST1, the gene mutant in vitelliform macular dystrophy (VMD), and two other BEST1-like genes, BEST2 and BEST4.
Bestrophins are transmembrane proteins that share a homology region containing a high content of aromatic residues, including an invariant arg-phe-pro (RFP) motif.
The bestrophin genes share a conserved gene structure, with almost identical sizes of the eight RFP–TM domain-encoding exons and highly conserved exon–intron boundaries.
Each of the four bestrophin genes has a unique 3′ end of variable length.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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