Thermo Fisher Scientific FBP11 Polyclonal Antibody
Western blot 및 Immunoprecipitation에 적합한 Rabbit Polyclonal Antibody. 인간 Formin-Binding Protein 11(PRPF40A) 타깃. 비결합(Unconjugated) 액상 형태로 제공되며, 4°C에서 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 275–325 of human Formin-Binding Protein 11 (PRPF40A, UniProt ID: O75400-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
FNBP3 (Formin-binding protein 3) is a 957 amino acid protein encoded by the human gene PRPF40A.
It belongs to the PRPF40 family and contains five FF domains and two WW domains.
These nuclear proteins, with both WW and FF interaction modules, bind to splicing factors and RNA polymerase II, linking transcription with splicing.
Through the WW domains, FNBP3 binds to Formin proline-rich regions.
Also known as Pre-mRNA-processing factor 40 homolog A, FNBP3 interacts with the WASL/N-WASP complex and suppresses its cytoplasmic translocation, thus inhibiting its cytoplasmic function.
FNBP3 is widely expressed in most tissues and localized to nuclear speckles.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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