Thermo Fisher Scientific FBP11 Polyclonal Antibody
Thermo Fisher Scientific FBP11 Polyclonal Antibody는 인간 FNBP3(Formin-binding protein 3)에 반응하는 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 액상 형태로 제공되어 안정적인 연구용 분석에 활용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 275 to 325 of human Formin-Binding Protein 11 (PRPF40A, UniProt ID: O75400-1, antigen length 957 aa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Phosphate/Tris citrate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt.
Target Information
FNBP3 (Formin-binding protein 3) is a 957 amino acid protein encoded by the human gene PRPF40A.
It belongs to the PRPF40 family and contains five FF domains and two WW domains.
Nuclear proteins with both WW and FF interaction modules bind to splicing factors and RNA polymerase II, potentially linking transcription with splicing.
Through WW domains, FNBP3 binds to Formin proline-rich regions.
Also known as Pre-mRNA-processing factor 40 homolog A, FNBP3 interacts with the WASL/N-WASP complex and inhibits its translocation to the cytoplasm, thereby suppressing its cytoplasmic function.
FNBP3 is widely expressed in most tissues and localized to nuclear speckles.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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