Thermo Fisher Scientific Histamine H3 Receptor (HRH3) Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:200

Immunohistochemistry (Frozen) (IHC (F))

• Tested Dilution: 1:100

Product Specifications

Product Specific Information

• Reconstitution: Add 50 µL or 0.2 mL double distilled water (DDW), depending on sample size.
• Ships as lyophilized powder at room temperature; store at -20°C upon arrival.
• Reconstituted solution can be stored at 4°C for up to 1 week.
• For long-term storage, aliquot and store at -20°C.
• Avoid multiple freeze/thaw cycles.
• Centrifuge all antibody preparations before use (10,000 × g for 5 min).

Target Information

Histamine H3 receptor regulates the release of neurotransmitters such as norepinephrine and somatostatin.
In histamine-containing neurons of the brain, it acts as a presynaptic autoreceptor, while in non-histamine neurons of both the central and peripheral nervous systems, it functions as a presynaptic heteroreceptor.
Multiple isoforms are generated by alternative splicing.
Histamine H3 receptor is primarily expressed in the brain, with ESTs isolated from brain (normal and cancer), breast cancer, colon cancer, and retinoblastoma libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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