Thermo Fisher Scientific RanBP1 Polyclonal Antibody
Rabbit 폴리클로날 RanBP1 항체로 Western Blot 및 Immunoprecipitation에 적합. Human RAN Binding Protein 1의 150–201번 잔기 영역을 면역원으로 사용. 1 mg/mL 액상 형태, 4°C 보관. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:5,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residues 150 and the C-terminus (residue 201) of Human RAN Binding Protein 1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
Ran/TC4-binding protein (RanBP1) interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kDa protein that binds to RAN complexed with GTP but not GDP. It does not activate GTPase activity of RAN but increases GTP hydrolysis by RanGAP1. The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In mammalian cells and yeast, RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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