Thermo Fisher Scientific POGK Polyclonal Antibody, MaxPab

Applications

• Western Blot (WB): 1–5 µg/mL

Product Specifications

Product Specific Information

Protein sequence:
MESTAYPLNL SLKEEEEEEE IQSRELEDGP ADMQKVRICS EGGWVPALFD EVAIYFSDEE WEVLTEQQKA LYREVMRMNY ETVLSLEFPF PKPDMITRLE GEEESQNSDE WQLQGGTSAE NEESDVKPPD WPNPMNATSQ FPQPQHFDSF GLRLPRDITE LPEWSEGYPF YMAMGFPGYD LSADDIAGKF QFSRGMRRSY DAGFKLMVVE YAESTNNCQA AKQFGVLEKN VRDWRKVKPQ LQNAHAMRRA FRGPKNGRFA LVDQRVAEYV RYMQAKGDPI TREAMQLKAL EIAQEMNIPE KGFKASLGWC RRMMRRYDLS LRHKVPVPQH LPEDLTEKLV TYQRSVLALR RAHDYEVAQM GNADETPICL EVPSRVTVDN QGEKPVLVKT PGREKLKITA MLGVLADGRK LPPYIILRGT YIPPGKFPSG MEIRCHRYGW MTEDLMQDWL EVVWRRRTGA VPKQRGMLIL NGFRGHATDS VKNSMESMNT DMVIIPGGLT SQLQVLDVVV YKPLNDSVRA QYSNWLLAGN LALSPTGNAK KPPLGLFLEW VMVAWNSISS ESIVQGFKKC HISSNLEEED DVLWEIESEL PGGGEPPKDC DTESMAESN

Target Information

This gene encodes a 134 kDa protein named strumpellin, predicted to have multiple transmembrane domains and a spectrin-repeat-containing domain. It is ubiquitously expressed, with the highest expression in skeletal muscle. The protein is associated with Strumpell disease, a form of hereditary spastic paraplegia (HSP), characterized by progressive lower extremity spasticity due to axonal degeneration. Over 30 loci (SPG1–33) have been implicated in HSP.

For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.