Thermo Fisher Scientific Thrombopoietin Polyclonal Antibody
Thrombopoietin 단백질을 인식하는 Rabbit Polyclonal 항체로, 인간, 마우스, 랫트 시료에 반응합니다. Western blot과 IHC(PFA)에서 사용 가능하며, 친화 크로마토그래피로 정제되었습니다. PBS/50% glycerol buffer에 보관되며, 연구용으로만 사용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human THPO (Accession P40225), corresponding to amino acid residues T257–F307 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2900672 |
Product Specific Information
This antibody detects endogenous levels of total THPO.
Target Information
Thrombopoietin (TPO, THPO, MPL ligand, megakaryocyte colony-stimulating factor) regulates platelet production by acting on hematopoietic cells committed to the megakaryocyte lineage. Binding of thrombopoietin to its receptor MPL (CD110) activates signaling pathways including JAK/STAT, MAPK, and PI3K/AKT, leading to megakaryocyte proliferation and differentiation, ultimately resulting in platelet formation (thrombopoiesis). Thrombopoietin is constitutively produced by the liver and has a predicted molecular weight of 38 kDa.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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