Thermo Fisher Scientific ZIC4 Monoclonal Antibody (1A9)
ZIC4 단백질을 표적으로 하는 Mouse monoclonal antibody (Clone 1A9). Western blot, IHC, ICC/IF, ELISA 등 다양한 응용에 사용 가능. 고순도 Affinity chromatography 정제, PBS buffer에 보존. 연구용으로만 사용.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 3 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 0.03 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A9 |
| Immunogen | ZIC4 (NP_115529, 249–319 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SDRKKHSHVH TSDKPYTCKV RGCDKCYTHP SSLRKHMKVH GRSPPPSSGY DSATPSALVS PSSDCGHKSQ V
Target Information
This gene encodes a member of the ZIC family of C2H2-type zinc finger proteins. Members of this family are important during development and have been associated with X-linked visceral heterotaxy and holoprosencephaly type 5.
This gene is closely linked to the gene encoding zinc finger protein of the cerebellum 1 on chromosome 3.
Heterozygous deletion of these linked genes is involved in Dandy-Walker malformation, a congenital cerebellar malformation.
Multiple transcript variants have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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