Thermo Fisher Scientific Phospho-ATP1A1 (Ser16) Polyclonal Antibody
Phospho-ATP1A1 (Ser16) 폴리클로날 항체로, 인간·마우스·랫트 시료에 반응. Western blot 및 IHC(P)용 검증. 항원 친화 크로마토그래피로 정제된 고순도 항체. Na+/K+-ATPase α1 서브유닛의 Ser16 인산화 부위 인식.
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Thermo Fisher Scientific Phospho-ATP1A1 (Ser16) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic phosphopeptide derived from human Na⁺/K⁺-ATPase α1 around phosphorylation site of Ser16 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long-term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553687 |
Product Specific Information
- Detects endogenous protein at molecular weight of 112 kDa
- Purity >95% by SDS-PAGE
Target Information
The protein encoded by this gene belongs to the family of P-type cation transport ATPases and to the Na⁺/K⁺-ATPase subfamily.
Na⁺/K⁺-ATPase is an integral membrane protein responsible for establishing and maintaining electrochemical gradients of Na⁺ and K⁺ ions across the plasma membrane.
These gradients are essential for osmoregulation, sodium-coupled transport of various molecules, and electrical excitability of nerve and muscle.
This enzyme is composed of two subunits: a large catalytic α subunit and a smaller glycoprotein β subunit.
The α1 subunit is encoded by multiple genes, and several transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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