Thermo Fisher Scientific IL2RB Monoclonal Antibody (OTI1D1), TrueMAB
인간 IL2RB(CD122)를 인식하는 마우스 단클론 항체로, Western Blot에 최적화됨. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 저장용액 포함. 면역학 연구용으로 T세포 신호전달 관련 단백질 분석에 적합.
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Applications
- Western Blot (WB): Tested dilution 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1D1 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 27–240 + Mouse FC of human IL2RB produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and exists in three forms:
- Low affinity form: Monomer of the alpha subunit, not involved in signal transduction.
- Intermediate affinity form: Alpha/beta heterodimer.
- High affinity form: Alpha/beta/gamma heterotrimer.
The intermediate and high affinity forms are involved in receptor-mediated endocytosis and mitogenic signal transduction. The CD122 gene encodes the beta subunit, a type I membrane protein.
Dysfunction of CD122 is associated with oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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배송/결제/교환/반품 안내
배송 정보
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