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Thermo Fisher Scientific IL2RB Monoclonal Antibody (OTI1D1), TrueMAB
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Thermo Fisher Scientific IL2RB Monoclonal Antibody (OTI1D1), TrueMAB

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인간 IL2RB(CD122)를 인식하는 마우스 단클론 항체로, Western Blot에 최적화됨. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 저장용액 포함. 면역학 연구용으로 T세포 신호전달 관련 단백질 분석에 적합.

카탈로그번호
TA812259
판매단위
pk
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마지막 업데이트 2025. 08. 02. 오전 09:19
Thermo Fisher Scientific TA812259 IL2RB Monoclonal Antibody (OTI1D1), TrueMAB 100 ul pk판매 단위 pk ·
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600,200원VAT 포함 660,220원

Thermo Fisher Scientific · Thermo Fisher Scientific IL2RB Monoclonal Antibody (OTI1D1), TrueMAB

Applications

  • Western Blot (WB): Tested dilution 1:500

Product Specifications

항목 내용
Species Reactivity Human
Host / Isotype Mouse / IgG1
Class Monoclonal
Type Antibody
Clone OTI1D1
Immunogen Human recombinant protein fragment corresponding to amino acids 27–240 + Mouse FC of human IL2RB produced in HEK293T cell
Conjugate Unconjugated
Form Liquid
Concentration 1 mg/mL
Purification Affinity chromatography
Storage Buffer PBS with 1% BSA, 50% glycerol
Contains 0.02% sodium azide
Storage Conditions -20°C, Avoid Freeze/Thaw Cycles
Shipping Conditions Ambient (domestic); Wet ice (international)

Target Information

CD122 (Interleukin 2 receptor) is involved in T cell-mediated immune responses, primarily expressed in the hematopoietic system and exists in three forms:

  • Low affinity form: Monomer of the alpha subunit, not involved in signal transduction.
  • Intermediate affinity form: Alpha/beta heterodimer.
  • High affinity form: Alpha/beta/gamma heterotrimer.

The intermediate and high affinity forms are involved in receptor-mediated endocytosis and mitogenic signal transduction. The CD122 gene encodes the beta subunit, a type I membrane protein.
Dysfunction of CD122 is associated with oligoarticular juvenile idiopathic arthritis and rheumatoid factor negative juvenile idiopathic arthritis.


For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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