Thermo Fisher Scientific GABRA2 Monoclonal Antibody (N399/19), PE
GABRA2 단백질을 검출하기 위한 PE 형광 접합 단일클론 항체. 인간, 마우스, 랫트 반응성. WB, IHC, ICC/IF에 사용 가능. 단백질 G 정제, 액상 형태, 1 mg/mL 농도. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (IHC) | Assay-dependent |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | N399/19 |
| Immunogen | Fusion protein amino acids 350–385 (Cytoplasmic C-terminus) of rat GABA-A Receptor Alpha2 |
| Conjugate | PE |
| Excitation/Emission Max | 565/576 nm |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | 95.64 mM phosphate / 2.48 mM MES, pH 7.4, with 0.5 M EDTA |
| Contains | No preservative |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932182 |
Available Formats
- Unconjugated (MA5-27702)
- APC (MA5-45725)
- FITC (MA5-45726)
- PerCP (MA5-45727)
- Custom conjugation available on request
Product Specific Information
A 1:100 dilution of MA5-45728 was sufficient for detection of GABA-A R, Alpha2 in 20 µg of mouse brain lysate by ECL immunoblot analysis using Goat anti-mouse IgG:HRP as the secondary antibody. Detects approximately 55 kDa. Does not cross-react with GABA-A Receptor Alpha1.
This antibody was formerly sold as clone S399-19.
Target Information
GABA is the major inhibitory neurotransmitter in the mammalian brain, acting at GABA-A receptors which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternatively spliced transcript variants encoding the same protein have been found for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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