Thermo Fisher Scientific Phospho-PSD-95 (Ser295) Polyclonal Antibody
PSD-95 단백질의 Ser295 인산화 형태를 특이적으로 인식하는 Rabbit Polyclonal 항체. Western blot 및 IHC(Paraffin) 실험에 적합. 인간, 마우스, 랫트 시료에 반응. 고순도 정제 및 -20°C 보관. 연구용 한정 제품.
- 카탈로그번호
- PA5104637
- 판매단위
- pk
카탈로그
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human DLG4 (Accession P78352), corresponding to amino acid residues around phosphorylated Ser295. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Sequential chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2816112 |
Product Specific Information
This antibody detects endogenous levels of PSD-95 only when phosphorylated at Ser295.
Target Information
Post Synaptic Density 95 kDa (PSD-95), also known as synapse associated protein 90 kDa (SAP90), is a membrane-associated protein found in the postsynaptic density of forebrain neurons and certain presynaptic structures in the cerebellum. PSD-95 contains three PDZ domains, an SH3 domain, and a guanylate kinase homology (GuK) domain. It plays a key role in clustering NMDA receptors and Shaker-type potassium channels at the synaptic membrane in CNS neurons. PSD-95 interacts with other proteins through PDZ domain binding, including those with T/SXV motifs and neuronal nitric oxide synthase (nNOS) via PDZ–PDZ interactions.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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