Thermo Fisher Scientific Ksp-Cadherin/CDH16 Monoclonal Antibody (CDH16, 2448)

Applications

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1–2 µg/mL

Peptide Array (Array)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• For immunohistochemistry (PFA fixed): incubate antibody for 30 min at room temperature.
• Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C, followed by cooling at room temperature for 20 minutes.

Target Information

Cadherins are a family of Ca²⁺-dependent adhesion molecules that mediate cell-cell binding, critical for structural maintenance and morphogenesis.
Cadherin-16 (Ksp-Cadherin) is a type I membrane protein expressed specifically in the kidney, localized to the basolateral membrane of renal tubular epithelial cells.
The human Ksp-cadherin gene (Cadherin-16) maps to chromosome 16q21–proximal 16q22, and the mouse gene is localized to a syntenic region of distal chromosome 8.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.