Thermo Fisher Scientific IL12RB1 Polyclonal Antibody
IL12RB1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot 및 IHC(P)에서 검증됨. Human 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. PBS buffer에 보관되며 장기 보관 시 -20°C에서 안정적.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:600 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within human IL-12RB1 aa 51–100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 40% glycerol, 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2932518 |
Target Information
The protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. It binds to interleukin 12 with low affinity and is part of the IL12 receptor complex. This protein forms a disulfide-linked oligomer required for IL12 binding activity. Coexpression with IL12RB2 leads to high-affinity IL12 binding sites and reconstitution of IL12-dependent signaling. Lack of expression of this gene results in immunodeficiency associated with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants encoding distinct isoforms have been reported.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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