Thermo Fisher Scientific CD66 (CEACAM) Monoclonal Antibody (D14HD11)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000

-

Immunocytochemistry (ICC/IF)

5 µg/mL

-

Flow Cytometry (Flow)

1.2 µg/1x10^6 cells

-

ELISA (ELISA)

1:200-1:400

-

Product Specifications

Host/Isotype

Mouse / IgG1

Class

Monoclonal

Type

Antibody

Clone

D14HD11

Immunogen

Immunization with extracted proteins of CEACAM5. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CD66 (CEACAM),uniProtId:P06731-1,ncbiNodeId:9606,antigenRange:1-702,antigenLength:702,antigenImageFileName:MA1-17761_CD66_CEACAM_P06731-1_House_mouse.svg,antigenImageFileNamePDP:MA1-17761_CD66_CEACAM_P06731-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

2 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_1073291

Product Specific Information

This antibody recognizes native human CEACAM1, 3, 4, 5, 6 protein expressed in transfected mammalian cells.

Target Information

The CD66 molecules are 180-200 kDa glycoproteins of carcinoembryonic antigen family. They are present on all blood granulocytes and some tissue macrophages, but are absent from other hematopoietic cells. The expression of CD66 increases significantly on granulocytes upon their activation. CD66a (BGP1, CEACAM1) and CD66d (CGM1, CEACAM3), as well as CEACAM2 and 4, are transmembrane proteins, whereas CD66c (CEAL, NCA, CEACAM6) and CD66e (CEA, CEACAM5), as well as CEACAM7 and 8, are anchored to the plasma membrane by C-terminal glycosylphosphatidylinositol (GPI) lipid moiety.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.