Thermo Fisher Scientific CD66 (CEACAM) Monoclonal Antibody (D14HD11)
CD66(CEACAM) 단백질을 인식하는 Thermo Fisher Scientific의 Mouse IgG1 단클론 항체. Western blot, ICC/IF, Flow cytometry, ELISA 등에 사용 가능. 인간 CEACAM1,3,4,5,6 단백질에 반응하며 연구용으로 적합.
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Applications 및 Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunocytochemistry (ICC/IF) | 5 µg/mL |
| Flow Cytometry (Flow) | 1.2 µg/1x10^6 cells |
| ELISA (ELISA) | 1:200–1:400 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Host/Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | D14HD11 |
| Immunogen | Extracted proteins of CEACAM5 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1073291 |
Product Specific Information
This antibody recognizes native human CEACAM1, 3, 4, 5, 6 proteins expressed in transfected mammalian cells.
Target Information
CD66 molecules are 180–200 kDa glycoproteins of the carcinoembryonic antigen family. They are present on all blood granulocytes and some tissue macrophages, but are absent from other hematopoietic cells.
Expression of CD66 increases significantly upon granulocyte activation.
CD66a (BGP1, CEACAM1), CD66d (CGM1, CEACAM3), CEACAM2, and CEACAM4 are transmembrane proteins, whereas CD66c (CEAL, NCA, CEACAM6), CD66e (CEA, CEACAM5), CEACAM7, and CEACAM8 are anchored to the plasma membrane by a C-terminal glycosylphosphatidylinositol (GPI) lipid moiety.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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