Thermo Fisher Scientific MRG15 Polyclonal Antibody, Biotin

Applications

Tested Dilution

Publications

Western Blot (WB)

2-4 µg/mL

-

Product Specifications

Species Reactivity

Mouse, Rat

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Peptide with sequence APKQDPKPKFQEGC (aa 2-14). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:MRG15,uniProtId:Q9UBU8-1,ncbiNodeId:9606,antigenRange:2-14,antigenLength:362,antigenImageFileName:PA5-142070_MRG15_Q9UBU8-1_Goat.svg,antigenImageFileNamePDP:PA5-142070_MRG15_Q9UBU8-1_Goat_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Biotin Biotin Biotin

Form

Liquid

Concentration

0.5 mg/mL

Purification

Ammonium sulfate precipitation

Storage buffer

TBS, pH 7.3, with 0.5% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2932732

Product Specific Information

Additional Information: This antibody is expected to recognise isoform 1 (NP_006782.1) and isoform 2 (NP_996670.1).

This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:128,000.

Target Information

MRG15 ia a component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histone H4 and H2A. This modification may both alter nucleosome-DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.