Thermo Fisher Scientific SART1 Polyclonal Antibody
SART1 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체로, Western blot 및 IP에 사용 가능. 인간에 반응하며, 마우스와 랫에서도 예측 반응. 항원 친화 크로마토그래피로 정제되었고, 4°C에서 보관.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 750 and 800 of Human squamous cell carcinoma antigen recognized by T cells |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage conditions | 4°C |
| Shipping conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat
Target Information
This gene encodes two proteins, the SART1 protein expressed in the nucleus of the majority of proliferating cells, and the SART1 protein expressed in the cytosol of epithelial cancers.
The SART1 protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet.
The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens.
The SART1 protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients.
This SART1 antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy.
The SART1 protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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