Thermo Fisher Scientific SART1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:2,000–1:10,000

Immunoprecipitation (IP)

• Tested Dilution: Assay-dependent

Product Specifications

Product Specific Information

• Recommended shelf life: 1 year from date of receipt
• Based on 100% sequence identity, this antibody is predicted to react with Mouse and Rat

Target Information

This gene encodes two proteins, the SART1 protein expressed in the nucleus of the majority of proliferating cells, and the SART1 protein expressed in the cytosol of epithelial cancers.
The SART1 protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet.
The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens.

The SART1 protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients.
This SART1 antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy.
The SART1 protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.