Thermo Fisher Scientific RELA Polyclonal Antibody
Human RELA(NF-κB p65) 단백질을 인식하는 Rabbit Polyclonal Antibody로 Western blot 및 IHC(Paraffin)에서 사용 가능. KLH 결합 합성 펩타이드(100–170 aa)로 면역 생성. 액상 형태, 1 mg/mL 농도, PBS/BSA/glycerol buffer로 안정화. 연구용으로만 사용.
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- TA890002
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- pk
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 | - |
| Miscellaneous PubMed (Misc) | - | View 1 publication |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide conjugated to KLH derived from within residues 100–170 of Human RELA (NFkB p65, UniProt ID: Q04206-1) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Nuclear factor kB p65 (NF-κB p65) is encoded by the RELA gene and located on chromosome 11 in humans. Also known as RelA, it belongs to the Rel family of proteins and forms a heterodimer with p50 or p52 subunits. Upon TNF-α receptor activation, IKK phosphorylates IκB, leading to its degradation and subsequent activation of NF-κB. NF-κB p65 plays a critical role in transcriptional regulation of the immunoglobulin κ gene in mature B-lymphoid cells.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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