Thermo Fisher Scientific NTRK1 Monoclonal Antibody (OTI5B6), TrueMAB
NTRK1(TrkA) 단백질을 인식하는 Mouse 모노클로날 항체로, Western blot 및 IHC(P) 검증 완료. Human 시료 반응성. Lyophilized 형태로 제공되며 재구성 후 1 mg/mL 농도 유지. 신경세포 발달 연구 및 TrkA 관련 신호전달 연구에 적합.
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- CF806413
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- pk
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5B6 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 440–796 of human NTRK1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
NTRK1 (TrkA) is a receptor tyrosine kinase belonging to the neurotrophic factor family, essential for development and maintenance of the mammalian nervous system. Upon neurotrophin binding, TrkA autophosphorylates and activates the MAPK signaling pathway, leading to cell differentiation.
Mutations in TrkA are associated with congenital insensitivity to pain with anhidrosis, self-mutilating behavior, mental retardation, and certain cancers.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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