Thermo Fisher Scientific CRIM2 Polyclonal Antibody
CRIM2 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot에 최적화되어 있습니다. Human, Mouse, Rat에 반응하며, 항원 친화 크로마토그래피로 정제되었습니다. PBS 용액에 0.02% sodium azide가 포함되어 있으며, 냉장 또는 냉동 보관이 권장됩니다.
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Applications
- Western Blot (WB): 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A 15 amino acid synthetic peptide near the carboxy terminus of human CRIM2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS |
| Contains | 0.02% sodium azide |
| Storage conditions | Maintain refrigerated at 2–8°C for up to 3 months. For long term storage, store at -20°C. |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2551763 |
Product Specific Information
- A suggested positive control is Jurkat cell lysate.
- PA5-34411 can be used with blocking peptide PEP-1453.
Target Information
CRIM2, also known as Kielin/chordin-like protein (KCP), is a novel enhancer of BMP signaling.
It binds to BMP7, a morphogen important for kidney development and repair of acute kidney injury, enhancing receptor binding.
CRIM2 has been suggested as a potential antifibrotic therapy in acute and chronic kidney injury.
It can also interact directly with activin or TGF-Beta1, suppressing activin- and TGF-Beta1-dependent transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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