Thermo Fisher Scientific ARHGAP22 Polyclonal Antibody
ARHGAP22 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot에서 사용 가능. Human, Mouse, Rat 시료에 반응하며, 항원 친화 크로마토그래피로 정제됨. 1 mg/mL 액상 형태로 제공되며, 단기 4°C, 장기 -20°C 보관 권장.
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Applications
Western Blot (WB)
- Tested dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 564–620 of human ARHGAP22 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2 |
| Contains | 0.05% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2553560 |
Product Specific Information
- Detects endogenous ARHGAP22 protein at approximately 77 kDa.
- Purity: >95% by SDS-PAGE.
Target Information
GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form.
ARHGAP22 (Rho GTPase activating protein 22), also known as RHOGAP2, is a 698-amino-acid cytoplasmic protein containing one Rho-GAP domain and one PH domain.
It functions as a GTPase-activating protein for Rac1, converting it to an inactive GDP-bound state.
Through interaction with ZNF161 (VEZF1), ARHGAP22 may play a role in transcription regulation.
Multiple isoforms of ARHGAP22 exist due to alternative splicing events.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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