
Thermo Fisher Scientific Laminin gamma-1 Polyclonal Antibody
Laminin gamma-1 단백질을 검출하기 위한 Thermo Fisher Scientific의 폴리클로날 항체입니다. Western blot과 IHC(P)에서 사용 가능하며, 인간·마우스·랫트 반응성을 가집니다. 항원 친화 크로마토그래피로 정제된 비결합 항체로, 연구용으로 적합합니다.
- 카탈로그번호
- PA579577
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 0.1–0.5 µg/mL
- Publications: [참고문헌 없음]
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 0.5–1 µg/mL
- Publications: [참고문헌 없음]
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Laminin gamma 1 (1566–1579aa KKQEAAIMDYNRDI) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 5 mg BSA |
| Contains | 0.05 mg sodium azide, 0.05 mg thimerosal |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2746692 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes are polymers of Laminins with stabilizing Type IV Collagen networks, Nidogen, and several proteoglycans. They are found under epithelial layers, around blood vessels, and surrounding muscle, peripheral nerve, and fat cells. Laminins influence cell proliferation, phenotype, migration, gene expression, and tissue architecture. Each Laminin is a heterotrimer of alpha, beta, and gamma chains that undergo secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and interact with Integrins and other receptors. The human Laminin gamma-1 gene maps to chromosome 1q31 and is widely expressed in basement membrane-producing tissues.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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