Thermo Fisher Scientific MMP3 Monoclonal Antibody (OTI2D9), TrueMAB
MMP3 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot과 IHC(P) 검증 완료. Human 시료 반응. 동결건조 형태로 제공되며, PBS(pH 7.3, 8% trehalose) 버퍼에 보존. 연구용으로 조직 재형성과 상처 치유 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2D9 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 246–477 of human MMP3 produced in E. coli. |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20 °C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7 K MWCO, 0.5 mL, Product #89882).
Target Information
MMP3 (stromelysin‑1) belongs to the peptidase M10A subfamily. It is secreted as a pro‑protein and activated by extracellular protease cleavage.
MMP3 binds zinc and calcium ions and exhibits metallo‑endopeptidase activity. The active enzyme degrades collagen, gelatin, fibronectin, and laminin, playing roles in wound repair and tissue remodeling.
Mutations in the MMP3 gene have been associated with coronary heart disease 6.
For Research Use Only. Not for use in diagnostic procedures or resale without authorization.
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