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Thermo Fisher Scientific Phospho-53BP1 (Ser25) Polyclonal Antibody
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인간 및 마우스 반응성을 가진 Rabbit Polyclonal 항체로, Ser25 위치의 인산화된 53BP1 단백질을 검출. Western blot, IHC, IP 등 다양한 응용에 적합하며 항원 친화 크로마토그래피로 정제됨. 4°C 보관, 연구용 전용.
- 카탈로그번호
- A300652A
- 판매단위
- pk
카탈로그
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마지막 업데이트 2025. 08. 05. 오전 12:07
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Thermo Fisher Scientific A300652A Phospho-53BP1 (Ser25) Polyclonal Antibody 100 ul pk판매 단위 pk ·
재고 확인 필요
735,100원VAT 포함 808,610원
Thermo Fisher Scientific · Thermo Fisher Scientific Phospho-53BP1 (Ser25) Polyclonal Antibody
Thermo Fisher Scientific Phospho-53BP1 (Ser25) Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000–1:10,000 |
| Immunohistochemistry (IHC) | 1:1,000–1:5,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000–1:5,000 |
| Immunoprecipitation (IP) | 1–4 µg/mg lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Phosphorylated synthetic peptide representing a portion of human p53 Binding Protein 1 around serine 25 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.20 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | TBS, pH 7.0–8.0, with 0.1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- For IHC, epitope retrieval with citrate buffer (pH 6.0) is recommended for FFPE tissue sections
Target Information
53BP1 (P53-binding protein 1) plays a critical role in tumor suppression and is a putative substrate of ATM kinase. Upon DNA damage, 53BP1 is phosphorylated and localizes to the sites of double-strand breaks. It may participate in checkpoint signaling during mitosis, enhance TP53-mediated transcriptional activation, and maintain genomic stability through DNA repair.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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