Thermo Fisher Scientific NPY Polyclonal Antibody

Applications

Immunohistochemistry (IHC)

• Tested Dilution: Not specified
• View 2 publications

Immunohistochemistry (Paraffin) (IHC-P)

• Tested Dilution: 1:1,000–1:2,000
• View publications

Product Specifications

Product Specific Information

• Heat-mediated antigen retrieval recommended prior to tissue staining.
• Predicted to react with sheep, rabbit, chicken, guinea pig, cow, pigeon, pig, zebrafish, and rhesus monkey based on sequence homology.

Target Information

This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase, regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.