Thermo Fisher Scientific UBF-1 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal UBF-1 항체. Western blot과 IHC(P)에서 사용 가능. 1 mg/mL 농도의 액상 형태로, 항원 친화 크로마토그래피로 정제됨. PBS/glycerol buffer에 보관하며, 4°C 단기, -20°C 장기 저장 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:500–1:1,000 | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | – |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 500–550 of human UBF-1 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2553396 |
Product Specific Information
- Detects endogenous UBF-1 protein at approximately 90 kDa.
- Purity >95% by SDS-PAGE.
Target Information
UBF-1 encodes a member of the HMG-box DNA-binding protein family.
This protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions.
It may also be involved in chromatin remodeling and pre-rRNA processing, regulated by phosphorylation and acetylation.
Multiple alternatively spliced transcript variants and pseudogenes have been identified on chromosomes 3, 11, and X.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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