Thermo Fisher Scientific SYP Monoclonal Antibody (OTI1B10), TrueMAB

Applications

Western Blot (WB)

• Tested Dilution: 1:4,000
• Publications: References

Immunohistochemistry (Paraffin) (IHC (P))

• Tested Dilution: 1:150
• Publications: References

Product Specifications

Product Specific Information

For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).

Target Information

Synaptophysin is a calcium-binding integral membrane glycoprotein found in presynaptic vesicles of nearly all neurons. It has four transmembrane domains and interacts with dynamin under high calcium conditions, suggesting a role in synaptic vesicle endocytosis. Synaptophysin regulates short- and long-term synaptic plasticity and is a widely used marker for nerve terminals and neuroendocrine tumor differentiation. Mutations in the gene are associated with X-linked mental retardation.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.