Thermo Fisher Scientific RFXANK Monoclonal Antibody (OTI2F12)
RFXANK 단백질을 표적으로 하는 Thermo Fisher Scientific의 마우스 모노클로날 항체. Western blot, IHC, ICC/IF, Flow cytometry 등 다양한 응용 가능. 고순도 Affinity Chromatography 정제, 1 mg/mL 농도, 안정적 PBS 기반 저장. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2F12 |
| Immunogen | Full length human recombinant protein of RFXANK produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2725220 |
Target Information
Major histocompatibility (MHC) class II molecules are transmembrane proteins that play a central role in immune system development and control.
The protein encoded by this gene, together with regulatory factor X-associated protein and regulatory factor-5, forms a complex that binds to the X box motif of certain MHC class II gene promoters and activates transcription.
Once bound to the promoter, this complex associates with the non-DNA-binding factor MHC class II transactivator, which controls cell type specificity and inducibility of MHC class II gene expression.
This protein contains ankyrin repeats involved in protein-protein interactions. Mutations in this gene are linked to bare lymphocyte syndrome type II, complementation group B.
Two transcript variants encoding different isoforms have been described, with only one isoform showing activation activity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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